Saha, Laky and Bhatttacharjee, Koushik and Mahapatra, Rima and Mukherjee, Rajnarayan and Basu, Keya and Medda, Shyamalendu and Pal, Atanu and Dasgupta, Sanjay and Bandyopadhyay, Arunansu (2024) A Rare Case of Proliferative Glomerulonephritis with Monoclonal IgG Deposits in an Adolescent Female; Mimicking Immune Complex Glomerulonephritis. Asian Journal of Case Reports in Medicine and Health, 7 (1). pp. 109-116.
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Abstract
Proliferative glomerulonephritis with monoclonal IgG deposits (PGNMID) is a rare renal disease under the spectrum of monoclonal gammopathy of renal significance (MGRS). Majority of the cases have been diagnosed in adult population, especially after the age of 40 years. We report a rare case of PGNMID in a 16 years old female, presented with nephrotic syndrome and active urine sediment. She had normal serum creatinine, low C3 and negative infective and autoimmune markers. Renal biopsy revealed membranoproliferative glomerulonephritis (MPGN) with monoclonal IgG3 kappa deposits. Our adolescent patient was treated with standard antiproteinuric therapy and steroid. Though C3 became normal on follow up, but proteinuria was increased and rituximab was added. Our case emphasizes the awareness by nephrologist and renal pathologist about this rare disorder even in adolescent population for accurate diagnosis, prognostication and treatment.
Item Type: | Article |
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Subjects: | Librbary Digital > Medical Science |
Depositing User: | Unnamed user with email support@librbarydigit.com |
Date Deposited: | 03 Aug 2024 05:44 |
Last Modified: | 03 Aug 2024 05:44 |
URI: | http://info.openarchivelibrary.com/id/eprint/1296 |