Incidence and risk factors of Pulmonary Complications after Cardiopulmonary bypass

Naveed, Anjum and Azam, Hammad and Ghulam Murtaza, Humayoun and Altaf Ahmad, Rana and Ahmad Raza Baig, Mirza (2017) Incidence and risk factors of Pulmonary Complications after Cardiopulmonary bypass. Pakistan Journal of Medical Sciences, 33 (4). ISSN 1681-715X

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Abstract

Objective: To determine the frequency of post-operative pulmonary complications (PPCs) after cardio-pulmonary bypass and association of pre-operative and intraoperative risk factors with incidence of PPCs.

Methods: This study was an observational analysis of five hundred and seventeen (517) patients who underwent cardiac surgery using cardiopulmonary bypass. Incidence of PPCs and risk factors of PPCs were noted. Logistic regression was applied to determine the association of pre-operative and intraoperative risk factors with incidence of PPCs.

Results: Post-operative pulmonary complications occurred in 32 (6.2%) patients. Most common post-operative pulmonary complication was atelectasis that occurred in 20 (3.86%) patients, respiratory failure in 8 (1.54%) patients, pneumonia in 3 (0.58%) patients and acute respiratory distress syndrome in 1 (0.19%) patients. The main risk factor of PPCs were advance age ≥ 60 years [odds ratio 4.16 (1.99-8.67), p-value <0.001], prolonged CPB time > 120 minutes [odds ratio 3.62 (1.46-8.97) p-value 0.003], pre-op pulmonary hypertension [odds ratio 2.60 (1.18-5.73), p-value 0.016] and intraoperative phrenic nerve injury [odds ratio 7.06 (1.73-28.74), p-value 0.002]. Operative mortality was 9.4% in patients with PPCs and 1.0% in patients without PPCs (p-value 0.01).

Conclusion: The incidence of post-operative pulmonary complications was 6.2% in this study. Advanced age (age ≥ 60 years), prolonged CPB time (CPB time > 120 minutes), pre-op pulmonary hypertension and intraoperative phrenic nerve injury are independent risk factors of PPCs after surgery.

Item Type: Article
Subjects: Librbary Digital > Medical Science
Depositing User: Unnamed user with email support@librbarydigit.com
Date Deposited: 26 Apr 2023 07:08
Last Modified: 12 Aug 2024 12:02
URI: http://info.openarchivelibrary.com/id/eprint/482

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