Soundharya, R. and Aruna, V. and Amruthavalli, G. V. and Gayathri, R. (2018) Cryptococcus neoformans – New Science for Discovering Melanin Modifiers. South Asian Journal of Research in Microbiology, 2 (3). pp. 1-4. ISSN 2582-1989
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Abstract
Aim: The present study was taken up to establish the effect of niacinamide on phenoloxidase lead melanogenesis and to prove the reliability of C. neoformans based screening methodology.
Methods: The organism was grown in the Minimal media in presence and absence of L- DOPA and Niacinamide and checked for its pigment producing ability at different time intervals.
Results: Niacinamide did not affect the pigmentation in Cryptococcus neoformans in the absence or presence of L-Dopa.
Conclusion: Cryptococcus neoformans as a biological tool for studying the mechanism of action of various melanin promoters/ inhibitors. The present study highlights the importance and usefulness of Cryptococcus neoformans based screening invention as it is cost effective rapid and ‘living cell model’.
Item Type: | Article |
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Subjects: | Librbary Digital > Biological Science |
Depositing User: | Unnamed user with email support@librbarydigit.com |
Date Deposited: | 10 May 2023 09:18 |
Last Modified: | 12 Aug 2024 12:02 |
URI: | http://info.openarchivelibrary.com/id/eprint/516 |