Assessment of the Effects of Moringa oleifera Oil, Anacardium occidentale Oil and Vitamin C and E on the Reticular Fibres of Cadmium- Induced Liver Damage in Wistar Rats

Background: Cadmium is one of the most toxic pollutants in the environment. This study aims at assessment of the effects of Moringa oleifera oil, Anacardium occidentale oil and vitamin C and E on the reticular fibres of cadmium- induced liver damage in wistar rats.

Methods: Thirty-five (35) wistar rats (80-180 g) were randomly selected and divided into seven groups of five rats each after acclimatization for two week. Group A served as control group received phosphate buffer, Group B received Cadmium only (3.5 mg/kg body weight). Group C received Vitamin C and Vitamin E, Group D received Vitamin C and Vitamin E and Cadmium. Group E received Cadmium and Moringa oleifera oil, Group F received Cadmium and Cashew nut oil and Group G received Cadmium (3.5 mg/kg body weight) and Moringa oleifera oil and Anacardium occidentale nut oil.

Results: Microscopic examination revealed normal histo- architecture of the liver, the portal vein and the reticular fibres were seen clearly and there was orderly arrangement of the reticular fibres in group A and in treatment groups B, C, D, E, F and G there was enlargement of the portal vein, distortion of reticular fibres and sinusoidal and restoration of the reticular fibres.

Conclusion: This therefore suggests that Moringa oleifera oil and Anacardium occidentale nut oil have ameliorative effects that led to the regeneration of the damaged and distorted reticular fibres.